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The description and level of evidence of included studies are shown in Table 1

Conclusions One phase III, multi-centre, single-arm, open-label trial with linked data from 4 predecessor studies was included

When overexpressed, MAO causes an excess of ROS in cells that injures mitochondria.[ref] Related article: MAO-A and MAO-B: Neurotransmitter levels, genetics, and studies SOD2 encodes an enzyme that converts ROS (reactive oxygen species) in the mitochondria

And honestly, for a lot of people, that kind of gradual, low-pressure approach is exactly what theyre looking for