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[DOI] [PubMed] [Google Scholar] [329].Jacobson EL

Many practitioners prefer gradual escalation in smaller increments than the 2.5 mg jumps used in clinical trials, particularly for researchers who experienced significant fatigue or body aches at prior dose increases

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Interestingly, moderate edema was already present at 25 minutes following paracetamol application, at the time of initiation of the generalized convulsions