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Levels of GSH in plasma and tissues were determined using HPLC 47 , using an assay that determines total GSH status

Oliveira, A

One difference between their model and the one reported here is that deletion of Gclc is induced in hepatocytes of adult mice (which are slowly proliferating), compared to theirs, where deletion of Gclc occurred in hepatocytes of growing animals (which are rapidly proliferating)

This creates a dangerous "metabolic trap." As the muscles siphon off the circulating BCAAs just to keep the lights on, the body's overall amino acid pool becomes severely depleted, halting tissue repair and triggering a cascade of neurological consequences

10.3390/toxins5040841 13 CaniP

Table prepared from various references