In addition, it has been revealed that pretreatment with lixisenatide suppressed expression of oxidative stress parameters (NO, GSH, MDA and catalase enzyme), apoptotic marker (caspase-3) and inflammatory marker (TNF-) in ischemic rat brains independent on GLP-1R mediation
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PMID: 18454811.
Tirzepatide is the active ingredient in Zepbound and Mounjaro, and its a dual-acting medication that works by mimicking two different hormones instead of just one: GIP and GLP-1