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In animal-model studies, BPC-157 administration has been associated with increased VEGF expression and enhanced vascularisation in target tissues

As a result, high-quality Real-World Data (RWD) and Real-World Evidence (RWE) are expected to play an increasingly important role in complementing clinical trial findings and supporting more informed, patient-centered healthcare decisions throughout the product lifecycle

However, certain lignans, such as gomisin B, gomisin C and gomisin G, are not BBB permeable, which may limit their use as central nervous system targets