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compared the effects of liraglutide and elafibranor on hepatic parameters in a dietary NAFLD mouse model and suggested that both elafibranor and liraglutide reduced body weight and improved insulin sensitivity and NAS

Approval timelines for novel compounds run 1218 months from complete submission under standard evaluation, or 6 months under priority review for conditions with unmet need

[13] Pharmacological options with robust evidence and regulatory approval include: Orlistat : A lipase inhibitor available over-the-counter or on prescription, suitable for adults with BMI 28 kg/m with comorbidities or 30 kg/m without

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In contrast, a recent network meta-analysis evaluated the efficacy of all currently available treatments for melasma

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