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However, many conventional treatments exhibit limited efficacy, adverse effects, poor compliance, and high relapse rates postdiscontinuation, necessitating rigorous clinical monitoring [19, 27]

We first examined the impact of 5FU treatment on mitochondrial abundance in the well-characterized CRC cell model HCT116

We further highlight the key areas where additional research is needed on this enigmatic plant and the consequences of its use

Similarly, suboptimal compliance with other medications may lead to suboptimal treatment outcomes, prolonged recovery times, and drug resistance development