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[17] Although animal and cellular models suggest that ALCs on neurotransmitter regulation, improvement in dysfunctional neuroplastic changes, and membrane modulation may play important role in the treatment of depression, more controlled trial data with adequately-powered, well-designed, and advanced methodology should be performed to conclude whether ALC as a monotherapy or supplementation agent may be clinically beneficial for MDD

doi: 10.3109/00365518509160995

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A randomized controlled trial published in the journal Nutrients found that women who were overweight or obese and took 3 g of CLA per day had significant reductions in total body fat after 12 weeks

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