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They are individually housed in metal cages in an air-conditioned room (22 2C, 55 5% humidity), under a 12 h light/12 h dark cycle with free access to food and water

Each peptide brings a different research emphasis, and the blend only makes sense if those emphases are complementary to the model under study

Whereas GLP-1 inhibits appetite and food intake, resulting in weight loss upon chronic administration, long-term GIP therapy generally is generally thought to have no effects on food intake (116)

GLP-1 drugs such as Ozempic and Mounjaro are now among the best-known peptides

Summary Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have emerged as a new antidiabetic drug class with multiple metabolic effects

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