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Autophagy 19 , 616631 (2023)

Not having enough folate during fetal development causes abnormalities of the brain, says Dr Edward Quadros, a professor in the department of medicine at SUNY Downstate who specializes in folate absorption

42 Another RCT studied cyano-B12, 1500 g three times per day for 2 weeks (route not reported), in patients with seasonal affective disorder and found no improvements in either the B12 or the placebo group

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But the margin between 'effective' and 'side effects dominate the experience' is narrow