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On the other hand, long-term aerobic glycolysis, called the Warburg effect, leads to cell swelling, metabolic disturbances, lack of ATP, and, depending on the type of cell, cell death through apoptosis or necrosis and possibly cancer (Schwartz et al., 2017

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Similarly, in the clinical setting, GLP-1RA treatment was associated with reduced oxidative stress markers such as 8-iso-prostaglandine-F2 (8-iso-PGF2), d-ROMs, superoxide, MDA, and lipid peroxides [80, 88, 89]

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