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Co-Primary Outcomes In the matched nave cohorts, 13% of tirzepatide ( N = 1399) and 11% of semaglutide initiators ( N = 1173) had baseline and follow-up HbA1c data
When you eat, these L-cells release GLP-1 into the bloodstream, where it performs several metabolic functions: signaling the pancreas to release insulin in response to rising blood glucose, slowing gastric emptying to promote satiety, and interacting with brain appetite centers to influence feelings of fullness