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3-AB is an early discovered PARP inhibitor, and its specificity is lower than newer PARP inhibitors developed for clinical use 176

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Glutathione helps regulate the body's inflammatory response by neutralizing free radicals and protecting cells from oxidative injury

Furthermore, Figure 4D confirmed that H 2 O 2 increased the content of cellular ROS, while both targeting peptides obviously reduced the fluorescence intensity of the cellular ROS probe compared to that of GHK, especially RGD-GHK inhibited approximately 40% of ROS production