Mechanically, inhibiting HDAC4 reduces the expressions of NGAL (a biomarker of renal injury), Bax, and cleaved caspase-3 expression, restoring the Klotho expression, thereby exerting renoprotective and anti-fibrotic effects (Shen et al., 2022a)
It is a sign that your body processes sublingual medication differently, and injectable delivery might serve you better
You do not have to tough it out if your side effects are impacting your quality of life
You can get vitamin B12 from sources like meat, fish, eggs and dairy products
Weight loss and dieting in general can affect nutrients, especially if youre not eating enough variety, but add in a fairly new medication, and its wise to monitor your nutrient levels while on GLP-1s
B6 and B12 : Support nerve function and brain health