Acromegalic patients often present with mild hyperphosphatemia despite increased GFR, due to increased TmP/GFR, which can be used as a comprehensive measure of disease status and can be reversed with treatment [107]
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There are also research findings that it affects mental health
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The semaglutide trial showed effect sizes "in the medium to large range," he said, although he urged caution about the results since the trial "was the first to look at this question in a controlled way." Semaglutide, sold by Novo Nordisk as Ozempic for type 2 diabetes and Wegovy for obesity, is part of a class of drugs known as GLP-1 receptor agonists, mimicking the hormone GLP-1 to reduce appetite, slow stomach emptying and regulate insulin