Quercetin demonstrated an increase in the RMSD till 50ns beyond which it suddenly peaked its value at 60 ns beyond which it stabilizes throughout the simulation with an average RMSD value of 0.31 nm (Fig
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10.1016/j.bbamcr.2019.118535 Biochim
About this article Cite this article Siddiqi, A.K., Khan, M.S., Kulkarni, A
Wheat proteins: a valuable resource to improve nutritional value of bread
This review integrates mechanistic insights with translational advances, outlining how dysregulation of chaperones, autophagy-mitophagy, the ubiquitinproteasome system, and ER stress pathways drive human diseases, while highlighting emerging therapeutic platforms, from pharmacological chaperones and autophagy modulators to targeted protein degradation technologies, CRISPR screens, spatial biology, and AI-guided drug discovery