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If this occurs: Allow additional time at room temperature (up to 30 minutes total) Very brief, gentle vortexing (35 seconds) as a last resort If aggregation persists, consider re-solubilizing in 10 mM HCl at a slightly lower concentration 6

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Each surgery type creates different anatomical and hormonal changes that affect how medications work

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Stage 3 CKD was most common based on eGFR or diagnosis codes (44.0%

Vezzani et al., 2011)