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doi: 10.1185/030079906X104786

Glutathione Constipation: Forms vs Risk Comparison Key Takeaways Glutathione constipation affects 2550% of users taking oral reduced L-glutathione at doses above 500mg daily, driven by suppression of enteric ROS signaling and microbiome shifts away from butyrate-producing bacteria

Tillmann S, Wegener G (2019) Probiotics reduce risk-taking behavior in the Elevated Plus Maze in the Flinders Sensitive Line rat model of depression

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Importantly, these benefits were seen across different conditions (obesity, Type 2 diabetes and even prediabetes) and ages

These include cognitive benefits such as mood elevation and improved learning ability