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Metabolic and cardiometabolic markers that may reflect the drug's activity include: Fasting blood glucose and HbA1c (particularly relevant in type 2 diabetes) Lipid profile (total cholesterol, LDL, triglycerides) Blood pressure Waist circumference Liver function tests, particularly in patients with metabolic dysfunction-associated steatotic liver disease (MASLD, previously termed NAFLD)

Furthermore, two studies revealed new molecular mechanisms for exendin-4 to affect MSC activities in myocardial infarction, which might present a hint for the same process in bone metabolism

(PubMed) Mennella JA, Beauchamp GK

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Pasteurized Akkermansia MucT

[23] 2 RSH RSSR + 2 H + + 2 e Disulfide formation stabilizes protein folded structure