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Pharmaceutics 2023;15

Both ATF4 and ATF3 bind to these elements, with ATF4 binding primarily to the ATF/CRE site and the ACM site, especially under stress conditions, while ATF3 binds to the ATF/CRE site in both basal and stress conditions

FIGURE 3 4 Robust synergistic therapy against cancer 4.1 Sensitized chemotherapy As a chemotherapeutic agent, platinum is one of the most widely used metal-based anticancer components (Makovec, 2019)

The Food and Drug Administration (FDA) has not approved BPC-157or the vast majority of lifestyle peptidesfor human use in any capacity

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