The STEP 1 extension trial, published in Diabetes, Obesity and Metabolism (Wilding et al., 2022), found that participants regained approximately two-thirds of the weight they had lost within one year of stopping semaglutide
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Most people experience only mild discomfort during self-injections, especially with SubQ injections that use smaller, finer needles
& Boyce, J
Gastroparesis: Because semaglutide slows gastric emptying, it is not recommended for use in patients with gastroparesis as it could worsen their condition
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