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Effect of food fortification on folic acid intake in the United States

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first, the N-terminal cysteine on Grx deglutathionylates PSSG via a thiol disulfide exchange reaction yielding PSH and a GrxSSG intermediate

The physiological significance of TXNRDs is further supported by the embryonic lethality of Txnrd1 or Txnrd2 knockout mice 52,53

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