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Effects of tirzepatide on cardiac injury and kidney function Treatment with tirzepatide resulted in a significant reduction in myocardial injury reflected by high-sensitivity troponin T as compared with placebo at both 24 and 52 weeks (ETD 24 weeks 9.8% (95% CI 16.0 to 3.3), P = 0.004, 52 weeks 10.4% (95% CI 16.7 to 3.6), P = 0.003), with no significant effect at 12 weeks (Fig

Understanding tirzepatide's relationship with liver function remains important for clinicians and patients, particularly those with pre-existing liver conditions or metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-alcoholic fatty liver disease (NAFLD)

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J Clin Med

Weight regain after discontinuing tirzepatide is common and well-documented