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In NCI-H716 human enteroendocrine cells, tetrapeptides, but not single amino acids or any of the dipeptides, tripeptides and pentapeptides tested, were found to induce a robust and selective [Ca 2+ ] i response associated with increased secretion of GLP-1 (Reference Le Nev and Daniel81)

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doi:10.1007/s13669-017-0187-1 Li Y, Hung SW, Zhang R, et al