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S.MohamedR
doi: 10.1016/j.bioteChadv.2020.107576
This background suggests that the optimal condition for a drug to be more efficient in carrying out its therapeutic action would be to cross a BBB with good vascular integrity and without further damage in the neuronal functional state
Nat Rev Drug Discov 10(4):292306 Priyadarsiny P, Khattar SK, Malik R, Udupa V, Seshaiah A, Rahman S, Shingatgeri VM, Bora RS, Saini KS (2008) Differential gene expression analysis of a known hepatotoxin, N -acetyl- p -amino-phenol (APAP) as compared to its non-toxic analog, N -acetyl- m -amino-phenol (AMAP) in mouse liver
Rats pretreated with the traditional liver tonics Andrographis paniculata (100-200 mg/kg/day) and Picrorhiza kurroa (50-100 mg/kg/day) had lower markers of liver damage (ALT, AST, lipid peroxidation) after acetaminophen intoxication (Nagalekshmi 2011
10.1074/jbc.M307525200 18 Contour-AnselD.Torres-FranklinM
