We dose conservatively, escalate based on tolerance rather than the calendar, use biweekly or split dosing when patients need it, and pair the medication with nutritional guidance and regular check-ins
Look M, Dunn JP, Kushner RF, Cao D, Harris C, Gibble TH et al (2025) Body composition changes during weight reduction with Tirzepatide in the SURMOUNT-1 study of adults with obesity or overweight
Aim to anchor each meal around a quality protein source: Lean meats like chicken and turkey Fish and seafood Eggs Greek yogurt and cottage cheese Beans, lentils, and tofu Because your appetite is smaller, a helpful strategy is to eat your protein first at meals, so that you get it in before you start feeling full and lose your appetite for the rest of the plate
doi: 10.1111/dom.14863 52
High Potency: Up to 1,000,000 stronger than BDNF in preclinical synaptogenesis assays
The finding suggests that OSA status may modify the survival advantage conferred by this therapy