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They specifically seem to tone down our response to the most rewarding things we encounter

When tirzepatide binds to GLP-1 and GIP receptors, it sends coordinated signals that can reduce appetite, slow gastric emptying and improve insulin responseworking together to enhance overall metabolic outcomes

(Hear Kimberly Ferrero discuss the article and more in a podcast episode of Actuary Voices )

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They are prepared using active ingredients under the direction of a prescribing clinician

doi: 10.1007/s00125-016-3896-5 181 LiuHZhanYLLuoGJZouLLLiYLuHY