Optimized dose-selective HDAC inhibitor tucidinostat overcomes anti-PD-L1 antibody resistance in experimental solid tumors
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2008;29(2 Suppl):S143-172
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Exclusion of other potential causes, such as immune, metabolic, infectious, toxic, and neoplastic conditions, via auxiliary tests
There are no signs of reactivity, instead there are observations of a generalised decrease in the density of astrocytes in cortical and subcortical areas, and even more prominent astrocytic depletion in the white matter