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6 Other side effects that have nothing to do with the stomach or bowel have also been reported, including hair loss (in around 5%) and mood changes

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Other recognized but rare complications of overdose include heart block, pancreatitis, acute renal failure, alopecia, leucopenia, thrombocytopenia, anaemia, optic nerve atrophy and acute respiratory distress syndrome [18, 50]

Reduce dose if sleep disruption is significant

Two common options are pen injectors and autoinjectors

[282] Timing of food intake relative to melatonin administration may affect absorption and should be considered when optimizing treatment effectiveness