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Yu Z, Jiang N, Su W, Zhuo Y

Abbreviations AEs: Adverse events NAEs: Neurological adverse events FDA: The Food and Drug Administration FAERS: The FDA Adverse Event Reporting System GLP-1 RAs: Glucagon-like peptide-1 receptor agonists ADRs: Adverse drug reactions PTs: Preferred Terms SOCs: System Organ Classes IQR: Interquartile range ROR: Reporting odds ratio CI: Confidence interval PRR: Proportional reporting ratio BCPNN: Bayesian Confidence Propagation Neural Network EBGM: Empirical Bayesian geometric mean EBGM05: The lower limit of 95% CI of EBGM IC: Information component IC025: The lower limit of 95% CI of the IC VANs: Vagal afferent neurons T2DM: Type 2 diabetes mellitus OR: Odds ratios References Targher, G., Mantovani, A

Surprisingly, a growing number of clinical studies demonstrate that these drugs (and other GLP-1 RAs) may have benefits that extend far beyond their original purpose, with their effects spanning the heart, kidneys, liver, and more

Sometimes, an underlying condition like hypothyroidism, polycystic ovary syndrome, or medication side effects from other drugs can limit the effectiveness of GLP-1 treatment

MTHFR Gene Mutation Test The MTHFR gene mutation test is a blood test that looks for the two most common gene mutations

[4] In differentiated 3T3-L1 mouse adipocytes, 5-Amino-1MQ lowered intracellular 1-MNA in a concentration-dependent manner with an EC 50 of 2.3 1.1 M (R = 0.94)