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Abbreviations : AD, Alzheimers disease

Obatoclax mesylate (GX15-070), which targets multiple Bcl-2 family proteins, including Mcl-1, has demonstrated anticancer activity in clinical trials for hematologic malignancies and induces both autophagy and apoptosis

[DOI] [PMC free article] [PubMed] [Google Scholar] 13.Bonuccelli G, De Francesco EM, de Boer R, Tanowitz HB, Lisanti MP

Oral Dis

Probiotics can interact with intestinal mucosal cells and other tissues to enhance their antioxidant defences

An overabundance of ROS disrupts intracellular redox balance, triggering oxidative stress and elevating susceptibility to ferroptosis