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Psarra A-MG, Sekeris CE (2009) Glucocorticoid receptors and other nuclear transcription factors in mitochondria and possible functions

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B-cell CLL/lymphoma 6 (Bcl-6), as the main transcription factor for Tfh differentiation, can directly inhibit gene expression of various factors in the glycolysis pathway by competing with IL-2 signaling (13).The metabolic characteristics of these cells are closely aligned with their phenotypic attributes, hinting at the possibility of manipulating T cell metabolism as a novel therapeutic strategy for inflammatory conditions (14)