However, clinical evidence is sparse, and further pharmacokinetic, stability, and dose-ranging studies are needed before translation
Pumori Saokar Telang (2013), Vitamin C in dermatology, National Library of Medicine
& Sklar, J
Despite advancements in metabolomics, which reveal changes in metabolites, a deeper understanding of the biological mechanisms behind these changes and metabolic regulatory processes is still lacking
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B-cell CLL/lymphoma 6 (Bcl-6), as the main transcription factor for Tfh differentiation, can directly inhibit gene expression of various factors in the glycolysis pathway by competing with IL-2 signaling (13).The metabolic characteristics of these cells are closely aligned with their phenotypic attributes, hinting at the possibility of manipulating T cell metabolism as a novel therapeutic strategy for inflammatory conditions (14)
