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Together, these data indicate that MV-carried OLFM4 acts as a secreted inhibitor for the Hippo signaling through a mechanism in which OLFM4 binds to extracellular domain of FAT1 to disrupt the interaction of FAT1 intracellular domain with MST1, thereby limiting MST1 activation (Fig
Current Knowledge on Beetroot Bioactive Compounds: Role of Nitrate and Betalains in Health and Disease
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GST overexpression and polymorphisms are seen in several cancers as well as other diseases, and have been implicated in resistance to chemotherapy 2,3
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