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However, a direct and reciprocal relationship among -syn accumulation, enteric inflammation, intestinal barrier impairment and PD onset has not yet been effectively established

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COMT also affects estrogen clearance in women connecting the Sexual Health and Women's Hormone pathways but its libido-relevant function is primarily through catecholamine neurotransmitter metabolism in limbic circuits

2021-April-15 2021;12(363)doi:10.3389/fendo.2021.650883