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GLP1 agonists like Semaglutide, Liraglutide may increase risk of pancreatitis, gastroparesis and bowel obstruction US: Researchers at University of British Columbia have found in a new study that that use of glucagon-like peptide-1 agonists for weight loss compared with use of bupropion-naltrexone was associated with increased risk of pancreatitis, gastroparesis, and bowel obstruction but not biliary disease

Dietary Trimethylamine N-Oxide Exacerbates Impaired Glucose Tolerance in Mice Fed a High Fat Diet

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Metformin users, common among type 2 diabetes patients who then add semaglutide, face a double hit since metformin independently reduces B12 absorption by 10-30% over long-term use

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