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By maintaining adequate GSH levels and GPX4 functionality, along with the efficient functioning of the system Xc , the antioxidant defense mechanism is strengthened, thereby suppressing ferroptosis and alleviating PF (Zhang T

It is also important to point out that unlike Grx1, Grx2 complexes iron (Fe), which is required to modulate its activity (Johansson et al., 2004

For human cohort data, demographic characteristics were compared using the Chi-squared test and Welchs t-test

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Growth Hormone-Releasing Peptide (GHRP) vs

After combined treatment with ginsenoside Rg1 and mannitol, p-PERK, p-eIF2, and ATF4 are downregulated, which effectively alleviates glutamate-induced neuronal ERS [115]