Anna Medaris is a Brooklyn-based freelance journalist with 15 years of experience covering health and lifestyle for publications including The Washington Post, Womens Health, Business Insider and US News & World Report.
Nat Commun 8:1177 Arbour KC, Jordan E, Kim HR, Dienstag J, Yu HA, Sanchez-Vega F, Lito P, Berger M, Solit DB, Hellmann M, Kris MG, Rudin CM, Ni A, Arcila M, Ladanyi M, Riely GJ (2018) Effects of co-occurring genomic alterations on outcomes in patients with KRAS-mutant non-small cell lung cancer
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In summary, alterations at the glutathione activator site result in an absent geometric and electrostatic complementary 3,50 for the reducing agent, explaining the inefficient reduction of numerous glutaredoxins 12,25,26,27,28,29,48 and thioredoxins by GSH
Brigelius-Flohe R