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Lactate is a preferential oxidative energy substrate over glucose for neurons in culture

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Within hepatocytes, GL is partially metabolized by lysosomal -D-glucuronidase to form 3MGA (Makino et al., 2008)

Functional enrichment (GO/KEGG) and Gene Set Enrichment Analysis (GSEA) revealed that GGCT knocking down significantly impacted pathways related to the cell cycle, oxidative stress, cell proliferation, and cell death in both cancers (Fig