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Glucose-dependent insulinotropic polypeptide (GIP), which reduces appetite and triggers the pancreas to release insulin

PMID: 21088638

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Scientific Activity It activates selected melanocortin G-protein-coupled receptor subtypes in research assays, engaging Gs, adenylyl cyclase, and cyclic AMP signaling

215 A higher level of NLRP3 inflammasome has been observed in microglial cells in the SN of PD patients, which has been linked to the secretion of pro-inflammatory cytokines associated with neurodegeneration

Prog Neurobiol 62:649671 Dunn WB, Bailey NJC, Johnson HE (2005) Measuring the metabolome: current analytical technologies