Hypersuccinylacetonaemia and normal liver function in maleylacetoacetate isomerase deficiency
Niki E, Yoshida Y, Saito Y, Noguchi N
For instance, NCOA4-mediated ferritinophagy may impact the activity of glutathione peroxidase 4 (GPX4), as increased iron levels can deplete intracellular antioxidants like glutathione, indirectly inhibiting GPX4 function and thereby facilitating ferroptosis (Mancias et al., 2014)
& Opsomer, G
Studies indicate that metformin treatment results in necrotic cell death, particularly in cancer cells treated with combined therapies, due to its ability to induce sustained energy stress and subsequent cellular damage
Vitamin C (Ascorbic Acid): Vitamin C (ascorbic acid), with its antioxidant properties and function in collagen formation, is an essential component for skin health