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doi: 10.1136/bmjdrc-2020-001905

32 B12 with folate, but not alone, led to significant improvements in cognitive function

These include extended-release formulations, combination therapies, and targeted molecular treatments designed to improve efficacy, minimize side effects, and enhance patient adherence

doi: 10.1002/smll.202107809 96 RanJLiuTSongCWeiZTangCCaoZet al

Cent Eur J Biol

Tolerance and Hedonic Adaptation Repeated exposure to the same rewarding stimuli leads to tolerance, requiring increasingly intense experiences to achieve similar pleasure levels