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Most GLP-1 receptor agonists are administered via injection, typically once a week

The results of the assessment showed that most of the included studies presented a low risk of bias across all domains of the Cochrane RoB 2 tool

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Here, it has been demonstrated for the first time that SEMA, a GLP-1RA with known pharmacological effects on metabolic syndrome [43, 44], is able to reshape PDAC stroma preventing T lymphocyte exclusion by P4HA1-collagen-pCAF axis (Fig