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Furthermore, the intracellular survival mechanism of the bacterium requires the involvement of each enzyme comprising the H 2 O 2 detoxification system, including GpoA, TpxD, and AhpD

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For diagnosis all of the following criteria should be fulfilled: Two or more periods (cycles) of intense, unremitting nausea and paroxysmal vomiting, lasting hours to days within a 6-month period