Since the carrier molecule of fatty acids, acyl-CoA, can not cross the cell membrane of the mitochondria, a deficiency of carnitine causes a reduction in the concentration of fatty acids in the mitochondria and, consequently, a reduced production of energy
Additionally, decreased intestinal cholesterol absorption in patients with insulin resistance and obesity may limit increases in LDL-C levels [15]
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112,113,114 The molecular mechanisms by which macrophage polarization is involved in the development of UC are shown in Fig
Cocaine intoxication is also associated with rhabdomyolysis, which can lead to acute renal failure