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Basis of Resubmission Rationale for the 2022 recommendation included evidence from 4 placebo-controlled, double-blind, randomized controlled trials (RCTs) that demonstrated that treatment with semaglutide 2.4 mg injection reduced body weight in individuals with an initial BMI of 30 kg/m 2 or greater (obesity) or 27 kg/m 2 or greater (overweight) in the presence of at least 1 weight-related comorbidity but did not demonstrate improvement in or prevention of weight-related comorbidities

We recommend sticking to bland, low-fat foods such as crackers, toast, rice, or applesauce, which can help ease nausea, as can ginger tea or small, frequent sips of water

Injection Route SubQ (subcutaneous) is the most accessible and practical

Lifestyle modifications like eating more nutrient-dense foods and exercising regularly can help maintain a healthy weight

Some patients may also experience support for energy utilization and lipid metabolism throughout treatment

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