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The broader GLP-1 class also remains under active legal scrutiny: more than 4,400 lawsuits have been filed against Eli Lilly and Novo Nordisk in multidistrict litigation alleging failure to warn about gastroparesis and vision loss linked to existing semaglutide and tirzepatide products, though neither orforglipron nor retatrutide is named in that litigation

On the other hand, diarrhea can cause irritation and inflammation in the anal area

In other cases, the urine sample is sent away for analysis

Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics, 2005, 1754(1-2): 253-262

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Ruggeri et al., in his research, suggested that the TPO antibody can be a marker and predictor of oxidative stress [19]