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Efficacy and safety of SGLT2 inhibitors with and without glucagon-like peptide 1 receptor agonists: a SMART-C collaborative meta-analysis of randomised controlled trials

Horm Metab Res 34: 504508, 2002

GLP-1 drugs work for most people, but some lose more weight than others, and not everyone has the same results

In models of high-fat diet-induced obesity, GLP-1R agonism has demonstrated the ability to enhance neurovascular coupling, improving the relationship between neuronal activity and blood flow in the brain

"People are familiar with the injections now

Graph showing lack of significant effect of acute treatment with incretin hormones on capsaicin sensitivity in adult rat DRG neurons (F)