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GIPs action to augment splanchnic blood flow, potentially affecting nutrient uptake and its involvement in adipose tissue metabolism and suggested central affects in the regulation of appetite as seen in animal models, all remain to be further explored in humans

PLoS One 16(4):e0249738

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Andrew Huberman notes that despite its popularity and extensive animal studies, there is only one poorly conducted human study, leaving much about its behavior in the human body, including its pharmacokinetics, still unknown 2

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