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GLP-1 drugs
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However, not everyone agrees
The antibody Fab7F38 appears to function by providing enhanced soluble surface area for crystal lattice packing, and indeed Fab7F38-bound GLP-1R can also assume an active conformation as shown by EM studies (see below), suggesting that Fab7F38 does not interfere with the conformational flexibility of the ECD during crystallization
Am J Physiol Regul Integr Comp Physiol 2016;311:R124-32.ArticlePubMedPMC 108
References Collaborators GBDO, Afshin A, Forouzanfar MH, Reitsma MB, Sur P, Estep K, et al
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